JPND JTC call 2022 - EU Joint Programme Neurodegenerative Disease Research

The EU Joint Programme – Neurodegenerative Disease Research (JPND) launches a transnational call aimed at understanding the mechanisms of non-pharmacological interventions.

The JPND, which aims to support transnational collaboration on neurodegenerative disease research, is launching a call for proposals on "Understanding the mechanisms of non-pharmacological interventions".

This joint transnational call is aimed at better understanding the mechanisms and biological substrates that underlie non-pharmacological interventions in order to tailor a holistic personalised treatment approach.

Proposals submitted under this call may include, but are not limited to, the following types of research:

  • Determining biomolecular and/or physical underpinnings of effects of non-pharmacological interventions;
  • Examining the mechanisms of effective non-pharmacological interventions at the molecular and cellular level by applying cutting-edge technologies;
  • Identifying the mechanisms of non-pharmacological interventions within the brain, using brain imaging, electrophysiology and other equivalent state-of-the-art techniques;
  • Identifying biological, psychological and social health markers and their associations to enable identification of modifiable risk factors amenable to non-pharmacological interventions and better predict and monitor the effects of these interventions for future large-scale clinical studies;
  • Elaborating modified concepts of non-pharmacological interventions with enhanced efficacy based on a deeper understanding of the mechanisms;
  • Identifying potential drug-target sites for a combination of pharmacological and non-pharmacological interventions;
  • Finding (individual) factors that predict response to interventions.

The neurodegenerative diseases addressed by the call are Alzheimer’s disease and other dementias, Parkinson’s disease and PD-related disorders, prion diseases, motor neuron diseases, Huntington’s disease, spinocerebellar ataxia and spinal muscular atrophy.

Pre-proposals must be submitted no later than 15:00 CET on 1 March 2022 via the electronic submission tool.

Full proposals must be submitted no later than 15:00 CEST on 28 June 2022 via the electronic submission tool.