Platforms for the promotion of translational and clinical research
Grants for multi-centric, population-based and disease-oriented studies with a longitudinal design (longitudinal studies) were given to research groups in Switzerland. The SNSF contribution complements funding of the host institutions and depends on the size of the study. As a rule, it may not exceed CHF 2 million per year.
Longitudinal studies help to establish research infrastructures dedicated to a topic of high relevance to the Swiss health system. Studies of this nature make it possible to collect and evaluate population-based and disease-related data over a long time period.
They explore a scientific question which may only be answered using a longitudinal approach over a time period that exceeds the funding periods stipulated in the SNSF project funding.
Currently supported longitudinal studies
Swiss HIV Cohort Study (SHCS)
Main applicant: Huldrych Fritz Günthard
The SHCS, established in 1988, is a longitudinal study enrolling HIV-infected individuals in Switzerland. It is a collaboration of all Swiss University Hospitals, smaller hospitals and private physicians. 75% of all antiretroviral treated persons in Switzerland participate. The major goal is to conduct research to optimize patient care, reduce HIV transmission and study HIV pathogenesis.
Swiss Transplant Cohort Study (STCS)
Main applicant: Jürg Ulrich Steiger
The Swiss Transplant Cohort Study (STCS) has become a tool for research and reporting in Swiss transplantation medicine. The STCS provides high-quality data and a network infrastructure for clinical and translational researchers to advance innovation and improve outcome of patients with solid organ transplantation.
Cohort study on Substance Use Risk Factors (C-SURF)
Main applicant: Gerhard Gmel
C-SURF investigates factors that influence behaviors related to the use of licit and illicit substances as well as other addictive behaviors such as gaming and gambling during the transition into adulthood, as well as the consequences of these behaviors on physical and mental health.
Swiss Atrial Fibrillation Cohort Study (SAFCS)
Main applicant: Stefan Osswald
The Swiss-AF cohort is an interdisciplinary research platform aiming to describe risk factors and morphological correlates for cognitive decline and dementia among patients with atrial fibrillation, the most common cardiac arrhythmia in the general population.
SAPALDIA Cohort on Healthy Aging (SAPALDIA)
Main applicant: Nicole Probst-Hensch
SAPALDIA is a Swiss-wide population-based longitudinal study established in 1991. The third follow-up aims to enrich longitudinally collected risk factors (personal; environmental), health phenotypes (respiratory; cardio-metabolic) and biomarker data (blood; genetic; DNA methylation) to improve understanding of biological aging.
Swiss Inflammatory Bowel Disease Cohort Study (SIBDCS)
Main applicant: Gerhard Rogler
The Swiss IBD Cohort Study (SIBDCS) is an association of Swiss gastroenterologists aiming at better understanding the causes and triggers of inflammatory bowel disease, identifying the concerns of those affected with the ultimate goal of improving their medical care.
The Swiss Hepatitis C Cohort Study (SCCS)
Main applicant: Francesco Negro
The Swiss Hepatitis C Cohort Study (SCCS) collects prospective data of ~5,000 persons infected with the hepatitis C virus (HCV). It functions as an infrastructure and investigative network fostering clinical and biomedical research on the natural history, pathogenesis and treatment of hepatitis C at a national level.
The Swiss National Cohort 2.0: a platform for longitudinal research in Switzerland (SNC)
Main applicant: Matthias Egger
The Swiss National Cohort (SNC) has anonymously linked census records with mortality data of the Swiss resident population since 1990. SNC research covers a wide array of public health issues, especially when combined with other cohorts and environmental data.
Cardiovascular diseases and psychiatric disorders in the general population: a prospective follow-up study (Psy-CoLaus)
Main applicant: Martin Preisig
CoLaus¦PsyCoLaus is a prospective longitudinal study of 6734 35 to 75 year-old subjects randomly selected from 2003 to 2006 in the general population of Lausanne. Its major goal is to elucidate the mechanisms underlying the comorbidity between mental disorders and cardiovascular risk factors or diseases.
You can find the detailed participation requirements in the regulations.
Submission of proposals
The evaluation ensured that the study can serve as a research platform for national and international research projects and that the data of the study is accessible for third-party research projects. Preconditions for this scientific exchange are that data is collected, analysed and secured according to international standards.
Panel Longitudinal Studies
The list contains the names of the members of the evaluation body Panel Longitudinal Studies. For the SNSF, interaction between applicants and members of evaluation bodies over applications is not compatible with academic best practices.
Previously supported longitudinal studies
The Swiss Venous Thromboembolism Cohort 65+ (SWITCO-65+)
Main applicant: Drahomir Aujesky
The objective of the SWIss Venous Thromboembolism COhort (SWITCO) 65+, a multicenter prospective longitudinal study, is to examine long-term outcomes and quality of life of 1003 elderly patients with acute venous thromboembolism.