JPND JTC Call 2021 - EU Joint Programme Neurodegenerative Disease Research

The EU Joint Programme – Neurodegenerative Disease Research (JPND): joint launches a transnational call on linking pre-diagnosis disturbances of physiological systems to neurodegenerative diseases.

The JPND, whichaims to support transnational collaboration on neurodegenerative disease research, is launching a call for proposals on "Linking pre-diagnosis disturbances of physiological systems to Neurodegenerative Diseases".

This joint transnational call will promote research aiming at the detection, measurement and understanding of early disease indicators related to neurodegenerative diseases, with potential for the development of new diagnostics or interventions.

Proposals submitted under this call may include, but are not limited to, the following types of research:

  • Demonstrating the relationship between early neurodegenerative processes and physiological disturbances, e.g. by analysing existing cohorts and longitudinal data.
  • Applying cutting-edge methods or technologies to improve the detection of early symptoms, e.g. by establishing innovative biomarkers and increasing the sensitivity, specificity and/or the robustness of the readouts.
  • Human or animal studies to decipher the neurodegeneration-derived processes causing early disease-specific signatures, e.g. at the neuropathological, cellular, synaptic, metabolic or inflammatory level. The use of well-characterised human cohorts’ data is encouraged.
  • Using digital technologies to link recognisable symptoms to physiological changes associated to neurodegeneration, e.g. by combining clinical, neurophysiological, biochemical, imaging and psychological data.
  • Relating prognostic signs of disease with real-life measurement of physiological disturbances using home-monitoring and/or wearable devices, including wireless sensors for patient monitoring.

The neurodegenerative diseases addressed by the call are Alzheimer’s disease and other dementias, Parkinson’s disease and PD-related disorders, prion diseases, motor neuron diseases, Huntington’s disease, spinocerebellar ataxia and spinal muscular atrophy.

Pre-proposals must be submitted no later than 15:00h C.E.T. on March 2, 2021, via the electronic submission tool.

Full proposals must be submitted no later than 15:00h C.E.S.T on June 29, 2021, via the electronic submission tool.

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