Home institution: University of Berne
The National Centre of Competence in Research (NCCR) "TransCure – From Transport Physiology to Identification of Therapeutic Targets" seeks to integrate the disciplines of physiology, structural biology and chemistry and to develop new therapeutic strategies for treating the most important diseases.
Transport proteins and ion channels play a key role in all physiological processes in the human body. Malfunctions in these proteins may contribute to the occurrence of diseases like diabetes, high blood pressure, osteoporosis and neuro-degeneration, and play a role in heart disease and cancers. The NCCR "TransCure" researchers aim to achieve a more profound understanding of the structures and mechanisms of these proteins. By broadening their knowledge of how transport proteins and channels work, they hope to develop new medicines.
Further information on the NCCR:
Management / Coordination
Dr. Valentina Rossetti
Institute of Biochemistry and Molecular Medicine
Phone: +41 (0) 31 631 36 22
NCCRs are financed through grants awarded by the SNSF, but also from other sources. The home institution involved in the NCCR also contributes a substantial amount of money. The available overall budget of the NCCR is further increased by monetary contributions from the project participants and third-party funds, which are generally invested by industrial companies.
The SNSF is financing the NCCR TransCure in its third funding period.
Financing 2010 – 2021 (Swiss francs)
Time-frame Funding source 2010 – 2013 2014 – 2017 2018 - 2021 SNSF grant 14’155’000 11'782'452 7'609’184 Funds of Berne University 4’590’667 4'349'751 4'760'128 Group funds of the project participants 13’846’209 12'680'191 9'109'697 External funds 335’080 656'305 579'355
Evaluation / Review Panel
For each NCCR, the SNSF appoints a Review Panel composed of renowned experts whose task it is to evaluate scientific quality and the progress made in NCCR projects. The Review Panel of the NCCR TransCure consists of the following experts:
Contact person at the SNSF:
National Centres of Competence in Research leave their mark on the research landscape well beyond the SNSF funding period. They help to define key topics and sustainably change Swiss research structures. Thus NCCRs can lead to the creation of new professorships and courses of study as well as new infrastructures or platforms at the universities involved.
NCCRs operate as a network in which a large number of scientific partners are active. Working within these networks has borne fruit in the form of new research approaches and excellent scientific contributions.
Structures created by this NCCR until now:
- Screening Platform
Contributions to society and the economy
The National Centres of Competence in Research not only engage in cutting-edge research, they also play an important role in transferring knowledge and new technologies to the economy and to society at large. They lead to the formation of start-ups, and the new insights have the potential to awaken the interest of politicians, globally active companies and the public at large.
Communication and knowledge transfer of the NCCR TransCure:
Promotion of academic careers and equal opportunities
The National Centres of Competence in Research consciously promote promising young researchers and are committed to equal opportunities for men and women in research.
Measures taken by the NCCR TransCure to promote young researchers and gender equality.